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If Your Dog Has Cancer, This Podcast Can Help
Chronic Lymphocytic Leukemia in Dogs

Chronic Lymphocytic Leukemia in Dogs │ Dr. Demian Dressler Q&A

What is Chronic Lymphocytic Leukemia, and how should we handle it in our dogs? Dr. Dressler tackles this question from Delisa in Alabama.

Episode Notes

Some cancers come for dogs right away, and others take longer. Chronic Lymphocytic Leukemia (CLL) can be hard to diagnose, because it often develops while the dog acts totally healthy. But routine blood tests can tip a veterinarian off that something is wrong … and when you know early there are lots of things you can do to help your dog. Today James Jacobson takes a question about CLL, also known as Lymphoid Leukemia, from Delisa in Alabama, and asks Dr. Dressler for an answer. Dr. Demian Dressler is co-author of our podcast sponsor, the book The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality and Longevity.

Links Mentioned in Today’s Show:

The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality and Longevity.

Apocaps can be found in many veterinary offices and online, including at

K9 Immunity can be found in many places online, including at

Delisa is a member of the private Facebook group for readers of Dr. Dressler’s book “The Dog Cancer Survival Guide”

Here’s a good article on lymphoid leukemia or lymphocytic leukemia on the National Canine Cancer Foundation’s website:

Here’s a good article that will help you to understand the difference among blood cancers, including chronic lymphocytic leukemia:

You can reach out to Dr. Demian Dressler directly on his veterinary hospital’s website:

Quick Overview of CLL from James Jacobson’s conversation with Dr. Nancy Reese:

First, let’s get clarity on this disease a little, because it’s often confused with a much more common dog cancer called lymphoma. To find out more, I asked one of our Full Spectrum veterinarians, Dr. Nancy Reese about Chronic Lymphocytic Leukemia, also known as Chronic Lymphoid Leukemia, or CLL for short.

I don’t have tape of our conversation about CLL, but you’ll hear from Dr. Nancy in an upcoming episode about Covid-19.

By email, Dr. Nancy explained that lymphoma and lymphocytic leukemia are both cancers of the lymphocytes.

What’s a lymphocyte? It’s a type of white blood cell that is born in the bone marrow, and less often, the spleen.

Those white blood cells circulate in the blood stream and the lymph system, fighting infections in cells all over the body. So, when lymphocytes get cancer, you’ve got a systemic disease, which means the cancer is everywhere by definition.

In lymphoma, the cancerous lymphocytes tend to collect in the lymph glands, which tend to get swollen.

In lymphocytic leukemia, the cancerous lymphocytes tend to circulate in the bloodstream.

Same cells, different locations in the body.

Either way, the cancer cells, the lymphoid or lymphocytic cells, are everywhere … so when you get this diagnosis, the veterinarian will almost always recommend chemotherapy. That’s the only conventional treatment that circulates in the blood and goes everywhere in the body, right?

So today’s question is this: when do you need to start the chemo for Lymphoid or Lymphocytic Leukemia? Right when you get the diagnosis? Or can you wait a while?

Well, the answer depends on whether the lymphocytic leukemia is acute or chronic!

Chronic conditions are long-developing, as opposed to severe and sudden, or acute conditions. Right? So Chronic Lymphocytic Leukemia is a long-developing cancer of lymphocytes. Also, Dr. Nancy added, the lymphocytes involved in CLL are mature and divide slowly, at the same rate as a normal cell. So that’s one reason this form of the cancer takes a long time to develop.

There is an acute form of lymphocytic leukemia, as well, that is much more immediately dangerous, and it develops in a immature form of the lymphocyte cells, a form that rapidly divides. So the Acute Lymphocytic Leukemia, or ALL, divides very fast, comes on suddenly, and rapidly progresses.

We’ll hear more from Dr. Nancy directly in an upcoming episode about coronavirus and dogs that is literally a must-listen. She’s the perfect person to ask about the pandemic we’re in right now, because she is not only a veterinarian with thirty years of experience under her belt, she’s also got a Ph.D. in Epidemiology.

About Today’s Guest, Dr. Demian Dressler:

Dr. Demian Dressler, DVM is internationally recognized as “the dog cancer vet” because of his innovations in the field of dog cancer management. A dynamic educator and speaker, Dr. Dressler is the author of the best-selling animal health book The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality and Longevity.

Dr. Dressler is the owner of the accredited practice South Shore Veterinary Care, a full-service veterinary hospital in Maui, Hawaii, Dr. Dressler studied Animal Physiology and received a Bachelor of Science degree from the University of California at Davis before earning his Doctorate in Veterinary Medicine from Cornell University.

“Your dog does NOT have an expiration date, and there are things ALL cancers have in common that you can help fight. Imagine looking back at this time five years from now and not having a single regret.”  - Dr. D

You can find hundreds of articles Dr. D wrote about dog cancer on his immensely popular website:

Follow Dr. D and The Dog Cancer Survival Guide on the Socials: 

Dog Cancer Answers is a Maui Media production in association with Dog Podcast Network

This episode is sponsored by the best-selling animal health book The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dog’s Life Quality and Longevity by Dr. Demian Dressler and Dr. Susan Ettinger. Available everywhere fine books are sold.

Listen to podcast episode for a special discount code.

If you would like to ask a dog cancer related question for one of our expert veterinarians to answer on a future Q&A episode, call our Listener Line at 808-868-3200.

Have a guest you think would be great for our show? Contact our producers at

Have an inspiring True Tail about your own dog’s cancer journey you think would help other dog lovers? Share your true tail with our producers.



Welcome to Dog Cancer Answers where we help you help your dog with cancer. Here’s your host, James Jacobson.

James Jacobson:

Hello, friend–welcome to Dog Cancer Answers: Today we look at a pretty rare cancer in dogs, Chronic Lymphocytic Leukemia—or CLL for short. CLL can be an unusual cancer because it may be diagnosed in an otherwise healthy-seeming dog and it can take a long time for the dog to start going downhill. The question we tackle today is when to start the big gun treatments like chemotherapy drugs. And what you can do before you need those.

This episode is one of our Q and A shows –where we take a question from one of our listeners and pose it to one of our dog cancer veterinary experts.

So what you are going to hear in this episode may not apply to you and your dog. However, if you do have a dog with CLL, I want to make sure you check out the show notes for this episode which contains a lot more information on the topic. (We try to make the show notes for every episode really helpful, but we did something a little different for today’s topic.)

We reached out to another veterinarian: Dr. Nancy Reese, one of our full spectrum vets –who you will hear from on a very timely episode we are recording this week about COVID-19 and your dog. We asked Dr. Nancy more about CLL and cancers of the lymphocytes. You will find all of that background information in the show notes.

For today’s show, our guest is Dr. Demian Dressler, coauthor of The Dog Cancer Survival Guide.

Today, Dr. Dressler takes a question from Delisa in Alabama.

Delisa Christy:

Good afternoon. Hi, thank you so much for taking my questions, just everybody that’s involved with this project, I’m just so grateful. [I] came across the information from your Cancer Guide and I’ve been nonstop studying. I’ve ordered the PDF and also, I’ve ordered the book. And we got the diet going.

My name is Delisa Christy, and I’m from Alabama, and I have a Pomeranian Sheltie mix. He’s five years old. His name is Zakk, Z-A-K-K, and he was just diagnosed seven days ago, as a matter of fact, by blood work. We went in to have his blood work for his annual checkup, no illness appeared. The blood work showed elevated white blood cells around fifty, with, also his lymphocytes around 45.

[It] was sent to a pathologist and the diagnosis is Chronic Lymphatic Leukemia. So my question is, I’ve ordered the Apocaps and also the K9 Immunity. I am also in the Facebook group. I do not usually see anything on anything with the blood disease. I see mostly on tumors. I just want to make sure I’m on the right path with the Apocaps, and make sure that that is also for leukemia. Thank you so much, and God bless you.

James Jacobson:

So what would you suggest to Delisa?

Demian Dressler:

Good question, Delisa. So, chronic lymphocytic leukemia is one of these that is often diagnosed in the exact same way that you just described: a perfectly healthy animal.

It’s a very, very slow, insidious disease and it takes a really long time for dogs to get sick from it, in general. And then the question becomes, well, when do you actually treat it using pharmaceuticals? And that’s usually lymphocyte counts right around 60,000, so you’ve still got some time.

You don’t really have to use chemotherapy drugs right now at this time, but I definitely would start to focus on everything that you can do to change what’s going on.

So that’d be dietary changes, and we talk about this in the book, which you’ll read: carbohydrate restriction, the addition of anti-cancer supplements, and vegetables.

To answer your question directly about Apocaps, I definitely do use Apocaps in my practice when I am helping to support normal apoptosis levels in dogs that do have Chronic Lymphocytic Leukemia, among other things, too.

But, what I would also try to remember is that you’ve got to go back in and get those white blood cell counts monitored, because it is progressive, but it’s really, really slow, and you may not need to do, necessarily, a lot of these big gun pharmaceuticals to help with the disease unless the white [blood] count gets above a certain point, and that can take a long time.

There’s also another test that you might consider called the PARR P-A-R-R test, and it’s a blood test, and that allows you to differentiate the leukemia cells into three different subtypes. Do you have T-cell, do you have B-cell, or do you have combined B-T cell — and that’s for Chronic Lymphocytic Leukemia.

And the reason why is because the T-cell ones are the least aggressive of the three, and then the other ones are more aggressive. And if you know that you’ve got a lesser, or more aggressive, cancer, that can help inform and guide your future treatment decisions, because it gives you a sense of urgency. So anyway, I hope that helps for the time being.

James Jacobson:

Thank you so much, Delisa, for your call.

Listeners, if you want to learn more about Chronic Lymphocytic Leukemia go to for the show notes and links that can help you.

Do you have a question like Delisa did? One of our veterinarians can answer it on a future episode of Dog Cancer Answers– please call our listener line at 808-868-3200 or visit our website at

On our website at, you can also listen to or download our back catalog. It’s the best way to help give you the information you need to help optimize your dog’s life quality and longevity.

We would like to thank our sponsor: The Dog Cancer Survival Guide book by Demian Dressler and Susan Ettinger. The book is available wherever fine books are sold both online and in physical bookstores. If you would like to help support this podcast, get it right away direct from the publisher, Maui Media. You can get the paperback with free shipping anywhere in the USA or the ebook edition for just $9.95. To get either the ebook or the paperback go to this website: And because you’re a listener to this show, if you use the promo code “podcast”, you can save 10%. The website again: Use the promo code “podcast” for 10% off. That is

I would like to thank Dr. Demian Dressler for being our guest today.

If you would like to reach him directly, his website is :

Until next time, I am James Jacobson. From all of us here at Dog Cancer Answers, I wish you and your dog a warm Aloha.


Thank you for listening to Dog Cancer Answers. If you’d like to connect, please visit our website at or call our listener line at 808-868-3200.

And here’s a friendly reminder that you probably already know: this podcast is provided for informational and educational purposes only. It’s not meant to take the place of the advice you receive from your dog’s veterinarian. Only veterinarians who examine your dog can give you veterinary advice or diagnose your dog’s medical condition. Your reliance on the information you hear on this podcast is solely at your own risk. If your dog has a specific health problem, contact your veterinarian. Also please keep in mind that veterinary information can change rapidly, therefore some information may be out of date.

Dog Cancer Answers is a presentation of Maui Media in association with Dog Podcast Network.

Dr. Demian Dressler


Maui, Hawaii, USA

More Episodes

Dr. Demian Dressler, DVM, is internationally recognized as “the dog cancer vet” because of his innovations in the field of dog cancer management. A dynamic educator and speaker, Dr. Dressler is the author of the best-selling animal health book The Dog Cancer Survival Guide.